Medical Council of Canada MCCQE Authorized Pdf - MCCQE Valid Exam Questions

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Medical Council of Canada MCCQE Part 1 Exam Sample Questions (Q76-Q81):

NEW QUESTION # 76
A 61-year-old man presents to the office for follow-up of recent laboratory test results. He has hypertension for which he takes amlodipine daily. His blood pressure is 148/94 mm Hg. His creatinine level is 140 µmol/L (normal 70-120), and his urine protein-to-creatinine ratio is persistently elevated. You would like to prescribe ramipril, but he refuses to take any additional medication. Which one of the following is the best next step?

A. Inform the patient that he eventually may need dialysis if he refuses the medication.
B. Provide the patient with free samples of ramipril.
C. Determine why the patient is refusing to take more medication.
D. Explain to the patient the importance of preventing the progression of his chronic kidney disease.
E. Agree to stop the patient's amlodipine if he takes ramipril.

Answer: C

Explanation:
Respecting patient autonomy requires understanding their perspective before offering persuasion or incentives. The best next step is to explore the reason for non-compliance. This builds rapport and informs a shared decision-making process.
Toronto Notes 2023 - ELOM, Patient-Centered Communication:
"When a patient refuses recommended treatment, explore the reason behind the refusal before proceeding.
Shared decision-making is crucial."
MCCQE1 Objectives - ELOM > Communication and Consent:
"Candidates must demonstrate an ability to explore reasons for treatment refusal before counseling or modifying management." Options B and C may follow later. Options D and E can undermine appropriate pharmacologic care or violate ethics if not consented.

NEW QUESTION # 77
A 55-year-old woman presents with a 6-month history of poor memory and impaired concentration. She has bipolar I disorder that has been treated with lithium carbonate for 4 years. She has gained a lot of weight since starting lithium. Physical examination findings are otherwise normal. She is concerned about her memory issues, but there are no other perception, mood, or cognition abnormalities. Which one of the following tests is most likely to have abnormal findings?

A. Liver function tests
B. Serum thyrotropin (thyroid-stimulating hormone) level
C. Creatinine clearance
D. Serum sodium level
E. Parathyroid hormone

Answer: B

Explanation:
Comprehensive and Detailed Explanation:
Lithium commonly causes hypothyroidism, which can lead to fatigue, cognitive slowing, weight gain, and memory impairment. Thyroid-stimulating hormone (TSH) levels are often elevated in such cases.
Toronto Notes 2023 - Psychiatry / Endocrinology:
"Lithium is associated with hypothyroidism and renal impairment. Monitor TSH regularly in patients on lithium therapy." MCCQE1 Objectives (Psychiatry > 71-5: Mood Stabilizers):
"Candidates must recognize the endocrine side effects of lithium, including hypothyroidism and the importance of TSH monitoring." Creatinine clearance (C) may also be affected but is less directly associated with memory issues. Liver function (A), sodium (D), and PTH (E) are not typically the first abnormal values in this presentation.

NEW QUESTION # 78
A 42-year-old man presents with a history of fatigue and weight loss. He looks unwell, has a darker than usual complexion and his liver is enlarged. He is also found to have marked glycosuria. Which one of the following is the most useful diagnostic test?

A. Serum ferritin
B. Serum cortisol
C. Serum alpha-1 antitrypsin
D. Hemoglobin A1c
E. Serum amylase

Answer: A

Explanation:
This presentation suggests hereditary hemochromatosis. Common features include hyperpigmentation ("bronze diabetes"), hepatomegaly, diabetes, fatigue, and elevated liver enzymes. Serum ferritin is a screening test for iron overload, and elevated levels support the diagnosis.
Toronto Notes 2023 - Endocrinology / Gastroenterology:
"Hemochromatosis presents with skin hyperpigmentation, hepatomegaly, diabetes, fatigue. Diagnosis begins with serum ferritin and transferrin saturation." MCCQE1 Objectives (Internal Medicine > Metabolic and Endocrine > 37-1):
"Candidates must investigate iron overload syndromes using ferritin and transferrin saturation." Cortisol (B) is for adrenal insufficiency. A1AT (C) is a liver disease cause but not typical here. Amylase (E) is for pancreatitis. A1c (A) would confirm diabetes but not the underlying cause.

NEW QUESTION # 79
A 72-year-old man reports that his wife says he has hearing trouble. Examination reveals that air conduction on the right side is less than on the left side and greater than bone conduction bilaterally. He hears a tuning fork placed on the top of his head better with his left ear. Which one of the following is the most appropriate next step in management?

A. Hearing aid.
B. Computed tomography scan of the head.
C. Audiometry.
D. Magnetic resonance imaging of the posterior fossa.
E. Wax removal from the ears by irrigation.

Answer: C

Explanation:
The patient demonstrates signs of asymmetric sensorineural hearing loss (SNHL). In Weber test, sound localizes to the better ear in SNHL. Air conduction > bone conduction on Rinne test bilaterally supports SNHL. Audiometry is the best next diagnostic step to quantify and characterize the hearing loss.
Toronto Notes 2023 - ENT, "Hearing Loss":
"Audiometry is the first-line investigation to distinguish conductive from sensorineural hearing loss and to assess severity and frequency involvement." MCCQE1 Objectives (Medicine > ENT > 20-1):
"Candidates must know the approach to hearing loss and interpret Weber and Rinne tests to guide investigations such as audiometry." Imaging (A, C) is reserved for red flags such as unilateral persistent SNHL, which may later prompt MRI to rule out acoustic neuroma. Wax removal (D) is for conductive loss. Hearing aids (E) are management, not diagnostic, and come after audiologic evaluation.

NEW QUESTION # 80
You are treating a 78-year-old man for recent onset of diarrhea, tenesmus, and minor bleeding when he wipes.
He has a history of prostate cancer that was treated by radiotherapy. Rectal examination findings are normal.
Colonoscopy reveals a pale rectum with ulcerations and areas of mucosal hemorrhage. Which one of the following is the most likely explanation for this clinical presentation?

A. Rectal cancer
B. Radiation proctitis
C. Ulcerative colitis
D. Diverticulosis
E. Recurrent prostate cancer

Answer: B

Explanation:
Radiation proctitis is a well-known complication of pelvic radiation therapy (e.g., for prostate cancer). It presents months to years after treatment with rectal bleeding, tenesmus, and mucosal ulceration on colonoscopy.
Toronto Notes 2023 - Gastroenterology, "Radiation-Induced GI Injury":
"Radiation proctitis presents with rectal bleeding, tenesmus, urgency. Colonoscopy shows pale, friable mucosa, ulcerations, and telangiectasia." MCCQE1 Objectives (Gastroenterology > 47-2: GI Bleeding and Complications):
"Candidates must recognize radiation proctitis based on history of radiation and characteristic endoscopic findings." Ulcerative colitis (B) usually starts younger and is more diffuse. Diverticulosis (C) affects the left colon and causes painless bleeding. Recurrent prostate cancer (D) and rectal cancer (E) would show mass or infiltration.

NEW QUESTION # 81
......

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Medical Council of Canada MCCQE Authorized Pdf - MCCQE Valid Exam Questions

Free PDF 2025 Medical Council of Canada MCCQE –Professional Authorized Pdf

Medical Council of Canada MCCQE Part 1 Exam Sample Questions (Q76-Q81):

Pass Guaranteed 2025 Perfect Medical Council of Canada MCCQE Authorized Pdf

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